Spotlight on Research
Classic Chicago Magazine – Champions for A Cure : Saturday, June 4th, 2022 The GI Research Foundation Annual Ball
Article by Jill Lowe So many of us have a loved one, know someone or know of someone with IBD...
The Importance of Good Ostomy Care, featuring Janice Colwell, Advanced Practice Nurse , Ostomy Clinic Director, The University of Chicago Medicine
Life with an ostomy is often a net-positive change for patients who have endured months or years...
Webinars Discuss New Treatment Options and Mental Health and IBD with David T. Rubin, MD and Alyse Bedell, PhD
The advent of new therapies also raises questions about which treatments are most effective for different kinds of patients and disease states. Dr. Rubin reviewed the most recent science about these treatment options, and how physicians decide among medical therapies for their patients.
Patient Profile: Shelly Miller “It’s important for me to give back wherever I can.”
Explains Miller, “Jan [Colwell], God love her, she just kept sticking with me and advocating for me. She went back and she said, ‘We cannot leave this 50-something year old woman, in the prime of her life and her career, in a place where she can’t work again, and she can’t live her life.’” Following corrective surgery for Miller’s stoma, she was able to make a full recovery without further complications.
Provider Profile: Janice Colwell, Advanced Practice Nurse, Powerful Advocate for Patients
Colwell encourages any patients who will undergo surgery to create a stoma to meet with an ostomy nurse and ensure that they get good follow-up care to help them avoid complications and correctly use their pouching systems.
GIRF In the News: Preparing for the Next Pandemic – Featuring David T. Rubin, MD
On January 14, 2022, David T. Rubin, MD, Joseph B. Kirsner Professor of Medicine, Co-Director of the UChicago Medicine Digestive Diseases Center and GIRF Lead Scientific Advisor, shared insights on the current state of the COVID-19 pandemic, its impact on healthcare workers, the Omicron and future variants, the possibility of herd immunity, and planning for future pandemics on Steve Dale’s Other World on WGN Radio.
Patient Spotlight: Reaching New Heights with PCT (Pacific Crest Trail), with PSC, and IBD: Adam Rubinberg with his mother, Amy Rubinberg
After enduring the altitude and the rigors of strenuous hiking in Colorado, Adam Rubinberg...
A Closer Look: Research Processes at the University of Chicago Medicine Featuring Michael Charlton, MBBS
““Perhaps our greatest strength in basic science research is with the microbiome [e.g., the bacteria that live in the gut]. We helped develop an animal model for liver disease that become one of the most widely utilized in the world, as it recreates lipid diseases in mice. That enables us, in the lab, to study causes of the liver disease and also ways to prevent and reverse it. In particular, Dr. Eugene Chang’s work with the Duchossois Family Institute [at the University of Chicago Medicine], discovered that mice that don’t have any microbes, animals that have been bred to be germ-free, and live in germ-free facilities, are totally resistant to fatty liver disease.”
Moving the Needle: Forward, to the Future!
On Thursday, December 2nd, more than one hundred GIRF supporters joined the University of Chicago Medicine Digestive Diseases Center online for the second presentation of Moving the Needle: An Update on GIRF’s Impact. Eight esteemed physician scientists shared latest research updates informing the treatment and care of inflammatory bowel disease (IBD), liver disease, colon cancer, celiac disease, as well as the impact of the gut microbiome on depression and anxiety.
Other Recent News
Welcome Back with the Associates Board Annual Cocktail Party: ReUnited for GI Health
“Just looking at this room tonight, it feels awesome to say we are here, together, and doing what the Associates Board does—raising money, and giving it to support research at the University of Chicago Digestive Diseases Center,” said Jordan Hirsch, AB President.
Should digestive diseases patients seek out anti-inflammatory foods?
Inflammation is a key concern for people living with many different digestive diseases and other health concerns. Walnuts, turmeric, flaxseeds, green tea, broccoli sprouts, fatty fish, olive oil, among many, many, others, are all touted by different research studies (of varying rigor) as having anti-inflammatory properties.
Research Spotlight: How Do We Assess Cancer Risk, and Prevent Cancer, and Improve Mortality? Featuring Sonia Kupfer, MD
Explains Kupfer, “Number one, we want to understand better how some of these chemopreventive agents are working. For example, there is good clinical-trials data that aspirin prevents colon cancer, specifically in Lynch syndrome. Now, we can look at how it works, and target those pathways. Secondly, we can determine who may respond best to which therapy, or who may have more response, and use that information to build more robust treatments. That’s the big vision here. But it’s early days right now.”
Meet Jackie Casey: New GI Research Foundation Executive Director Shares Her Story
As a teenager, my brother began to suffer from what doctors then thought was ulcers as well. Blamed on diet and stress, his suffering went misdiagnosed and untreated for more than a decade. Finally, he was diagnosed with Crohn’s disease. His disease was resistant to the new and evolving biologic treatments. His life and work suffered constant disruption. Eventually after hospitalizations, he would have surgery to remove part of his large intestine. After a six week stay in the hospital fighting sepsis and other complications, he would return home to begin another course of treatment for maintenance. This too would eventually fail. Another surgery resulted in an ostomy that has mostly eliminated his symptoms and given him his life back.
New Equipment Funded by the GI Research Foundation at the 61st Annual Ball
GeoMX Digital Spatial Profiler “Like being inside a tissue sample at a molecular level” Maps the...
Research Spotlight: Cambrian Liu, PhD, On Reprogramming Stem Cells to Treat Inflammatory Bowel Disease
Explained Dr. Liu, “Consider that a disease flare is like a forest fire, and the drugs we have in our arsenal are firefighters. What no drug does currently is focus on the restoration of the intestine after a flare.”
Research Spotlight: Sonia Kupfer, MD, the Role of Bile Acids in Colorectal Cancer Disparities
“In order to achieve our goal of reducing the burden of GI cancers, we practice and strive for early detection and personalized medicine. Personalized medicine moves away from one-size-fits-all approaches, and integrates knowledge about a person’s genetics, personal and family history, and environmental risk factors, to provide tailored care to the individual.”
David T. Rubin, MD on The Power of Inquiry at the 61st Annual GIRF Ball
“GIRF has, as it always has, kept its eyes on the bigger picture as we have worked to develop our largest endeavor ever: our regenerative medicine program. As mentioned briefly last year during this Ball, regenerative medicine is the study of how tissues develop and mature into different organs, and how tissue injury occurs and changes with age or disease can be repaired or replaced. The potential applications for such a program are incredibly exciting, and may include tissue healing in inflammatory bowel disease, and organ regeneration in intestinal, liver, or pancreas failure conditions. Ultimately, these discoveries will yield new insights and treatments for GI cancer as well.”
A Triumphant Return: GIRF Champions for a Cure Ball
On Saturday, June 4, 2022, the GI Research Foundation Champions for a Cure Ball celebrated the courageous patients and devoted physician-scientists fighting to prevent, treat, and cure digestive diseases. Held at The Geraghty, a chic event space in Pilsen, the event marked the triumphant return to an in-person gala experience, and was a smash success – raising $1.5 million for research at the University of Chicago Medicine Digestive Diseases Center.